Skin & non-surgical
Skin boosters in Korea
Skin boosters are injections that place small amounts of an ingredient such as polynucleotide (Rejuran Healer) or hyaluronic acid into the skin, used for texture, dryness and fine lines rather than volume. They suit dull or thin skin. The partner clinic in Seoul applies numbing cream first, lists under 30 minutes for the treatment, and daily life carries on.
Who is a good candidate for skin boosters?
- Your skin looks dull or dry and feels rough, the concern the clinic names
- You have fine lines, for example around the eyes, rather than deep folds
- You want a treatment with little visible downtime that fits a short trip
- You are comfortable with a gradual change, knowing that the studies so far are small
When it may not be the right choice
- You want to fill hollows or deep folds. That is what dermal fillers do
- Your skin sags. Skin boosters do not lift loose skin
- You have an infection, a rash or a cold sore where the injections would go
- You expect a clear change from a single visit. Results vary between people
Which method fits you?
Skin booster is a broad name with no single agreed definition: a 2024 review describes it as covering many ingredients injected to improve the condition of the skin rather than its volume. The clinic offers three Rejuran products and chooses one for your skin and the area. Rejuran is a sodium polynucleotide product made by PharmaResearch in Korea; polynucleotides are purified DNA fragments taken from salmon.
| Method | What happens | Suits | Downtime |
|---|---|---|---|
| Rejuran Healer | The standard polynucleotide product, which the clinic uses across the whole face. | Dull, dry skin and fine lines, as the clinic lists | Small bumps and redness at the needle points, usually easing within a day or two |
| Rejuran i | A thinner version that spreads easily, which the clinic uses around the eyes. | Fine lines and thin skin around the eyes | Bruising shows more easily in this thin skin |
| Rejuran HB | Polynucleotide mixed with hyaluronic acid and a local anesthetic, according to the clinic. | Skin that needs more hydration, as the clinic describes it | Similar small bumps and redness |
What happens on the day of skin boosters?
- Consultation. The doctor looks at your skin and chooses the product and the areas to treat.
- Numbing cream goes on and is left for a while before the injections.
- Many small injections go into the skin across the planned areas, in under 30 minutes by the clinic’s listing.
- Afterwards you can return to your plans. According to the clinic, the effect can be checked about 7 to 10 days later.
What is recovery like after skin boosters?
- Same day
- Small raised bumps, redness and a stinging or burning feeling at the needle points. A consensus report on polynucleotide injections also describes occasional small bruises.
- Days 1 to 2
- The bumps flatten and the redness fades. The same report advises keeping out of sunlight and away from sun lamps for 48 hours.
- Days 7 to 10
- The clinic says this is when the effect can be checked.
- Months 1 to 3
- Studies usually give more than one session. In one study of injections around the eyes, the clearest change was seen 3 months after two sessions.
How long should you stay in Seoul after skin boosters?
A skin booster session needs no stitches or return visit at the clinic, and you can carry on with your day. Have the injections early in your stay so the small bumps have settled before you fly, and leave makeup off the needle points until the clinic clears it. If you plan more than one session, ask how far apart they should be, because a second session may fall after you are home. If redness around the needle points keeps spreading, or you notice heat, pus or a fever, it can mean an infection: contact the clinic straight away, or see a doctor promptly if you are already home.
What are the risks of skin boosters?
- Small raised bumps at the needle points, more noticeable when the product is placed in the top layer of the skin
- Redness, swelling, a burning feeling and small bruises
- Pain during the injections, eased by numbing cream
- Infection at the injection points
- Little or no visible change for some people. The studies are small and use different methods, so results are hard to predict
What affects the cost of skin boosters in Korea?
What a skin booster costs depends on the product (Rejuran Healer, Rejuran i or Rejuran HB), the amount, the areas and the number of sessions; we do not publish prices for skin boosters. A patient coordinator answers first, then the surgeon at the partner clinic that fits your case reviews your photos and consults in depth. If more than one session is planned, have the product, the amount and the session count written down before the first injection. Our consultation is free for you, and you pay only the clinic’s own price for treatment.
More questions
What is Rejuran Healer made of?
Rejuran is a polynucleotide product made by PharmaResearch in Korea. Polynucleotides are purified DNA fragments taken from salmon. The clinic also offers Rejuran i for the eye area and Rejuran HB, which it says contains hyaluronic acid and a local anesthetic.
How many skin booster sessions will I need?
There is no fixed number. Studies of polynucleotide injections often use more than one session, and the doctor plans yours for your skin. If you can visit only once, ask the doctor what one session can realistically do for your skin.
Are skin boosters the same as fillers?
No. Fillers add volume to hollows and folds. Skin boosters put small amounts of product into the skin itself, for texture and dryness, and do not fill deep lines.
Do skin boosters hurt?
There are many small injections, so numbing cream is used first, and the clinic says Rejuran HB contains a local anesthetic. In one split-face study, injecting slightly deeper caused less pain and fewer bumps than injecting into the top layer of the skin.
Related procedures
Sources
- Clinic figures as published by Urban Plastic Surgery, collected October 3, 2026. Your surgeon confirms your own plan.
- Skin boosters: Definitions and varied classifications. PubMed Central, US National Library of Medicine
- Efficacy and Safety of Intradermal Versus Subdermal Injection of Polynucleotide for Facial Improvement: A Prospective Split-Face Study. PubMed Central, US National Library of Medicine
- Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides. PubMed Central, US National Library of Medicine
- The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review. PubMed Central, US National Library of Medicine
- Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine. PubMed Central, US National Library of Medicine
Cases and clinic figures come from our partner clinic, Urban Plastic Surgery. The partnership does not change what we publish about risks and recovery.